R100C (p.Arg100Cys) variant of DRD3 (Dopamine receptor D3)
R100C (p.Arg100Cys) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
R100C (p.Arg100Cys) variant details
- p.Arg100Cys
- Ensembl rs1559992771
- Missense
- Variant Prioritization Score for Impact Estimate 0.749
- REVEL 0.82
- ESM-1b 1.00
- AlphaMissense 0.28
- MetaLR 0.68
- MetaSVM 0.62
- CADD 30.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available