N47S (p.Asn47Ser) variant of DRD3 (Dopamine receptor D3)
N47S (p.Asn47Ser) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
N47S (p.Asn47Ser) variant details
- p.Asn47Ser
- cosmic curated COSV55678
- Missense
- Variant Prioritization Score for Impact Estimate 0.847
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 0.97
- MetaLR 0.97
- MetaSVM 1.08
- CADD 25.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available