N12K (p.Asn12Lys) variant of DRD3 (Dopamine receptor D3)
N12K (p.Asn12Lys) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
N12K (p.Asn12Lys) variant details
- p.Asn12Lys
- cosmic curated COSV10609
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.27
- ESM-1b 1.00
- AlphaMissense 0.24
- MetaLR 0.24
- MetaSVM -0.64
- CADD 22.90
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available