M52L (p.Met52Leu) variant of DRD3 (Dopamine receptor D3)
M52L (p.Met52Leu) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
M52L (p.Met52Leu) variant details
- p.Met52Leu
- cosmic curated COSV55682
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.06
- MetaLR 0.02
- MetaSVM -1.03
- CADD 10.60
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available