M52K (p.Met52Lys) variant of DRD3 (Dopamine receptor D3)
M52K (p.Met52Lys) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes structural context.
M52K (p.Met52Lys) variant details
- p.Met52Lys
- ExAC rs201882973
- TOPMed rs201882973
- gnomAD rs201882973
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.17
- ESM-1b 1.00
- AlphaMissense 0.55
- MetaLR 0.10
- MetaSVM -0.99
- SIFT 0.00
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available