M52I (p.Met52Ile) variant of DRD3 (Dopamine receptor D3)
M52I (p.Met52Ile) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
M52I (p.Met52Ile) variant details
- p.Met52Ile
- cosmic curated COSV55681
- ExAC rs763684802
- gnomAD rs763684802
- cosmic curated COSV11413
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.10
- ESM-1b 1.00
- AlphaMissense 0.11
- MetaLR 0.02
- MetaSVM -1.07
- CADD 7.83
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available