L89Q (p.Leu89Gln) variant of DRD3 (Dopamine receptor D3)
L89Q (p.Leu89Gln) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
L89Q (p.Leu89Gln) variant details
- p.Leu89Gln
- ExAC rs753115718
- gnomAD rs753115718
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.59
- ESM-1b 1.00
- AlphaMissense 0.29
- MetaLR 0.20
- MetaSVM -0.75
- CADD 27.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available