L7Q (p.Leu7Gln) variant of DRD3 (Dopamine receptor D3)
L7Q (p.Leu7Gln) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L7Q (p.Leu7Gln) variant details
- p.Leu7Gln
- gnomAD rs1444191780
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.27
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.18
- MetaSVM -0.92
- CADD 23.20
- Most common in the South Asian population (allele frequency 1.5e-05)
- Structural context available