L60R (p.Leu60Arg) variant of DRD3 (Dopamine receptor D3)
L60R (p.Leu60Arg) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
L60R (p.Leu60Arg) variant details
- p.Leu60Arg
- ExAC rs747070751
- gnomAD rs747070751
- Missense
- Variant Prioritization Score for Impact Estimate 0.71
- REVEL 0.75
- ESM-1b 1.00
- AlphaMissense 0.98
- MetaLR 0.49
- MetaSVM 0.38
- CADD 27.70
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available