L60P (p.Leu60Pro) variant of DRD3 (Dopamine receptor D3)
L60P (p.Leu60Pro) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
L60P (p.Leu60Pro) variant details
- p.Leu60Pro
- ExAC rs747070751
- gnomAD rs747070751
- Missense
- Variant Prioritization Score for Impact Estimate 0.733
- REVEL 0.79
- ESM-1b 1.00
- AlphaMissense 1.00
- MetaLR 0.49
- MetaSVM 0.38
- CADD 28.20
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available