L119V (p.Leu119Val) variant of DRD3 (Dopamine receptor D3)
L119V (p.Leu119Val) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L119V (p.Leu119Val) variant details
- p.Leu119Val
- gnomAD rs1162323018
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.32
- ESM-1b 1.00
- AlphaMissense 0.72
- MetaLR 0.20
- MetaSVM -0.83
- CADD 24.50
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available