L119F (p.Leu119Phe) variant of DRD3 (Dopamine receptor D3)
L119F (p.Leu119Phe) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L119F (p.Leu119Phe) variant details
- p.Leu119Phe
- gnomAD rs1162323018
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.19
- ESM-1b 0.74
- AlphaMissense 0.45
- MetaLR 0.16
- MetaSVM -0.95
- CADD 23.50
- Most common in the Finnish in Finland (FIN) population (allele frequency 7.5e-05)
- Structural context available