I124T (p.Ile124Thr) variant of DRD3 (Dopamine receptor D3)
I124T (p.Ile124Thr) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
I124T (p.Ile124Thr) variant details
- p.Ile124Thr
- ExAC rs200897022
- TOPMed rs200897022
- gnomAD rs200897022
- Missense
- Variant Prioritization Score for Impact Estimate 0.833
- REVEL 0.92
- ESM-1b 1.00
- AlphaMissense 1.00
- MetaLR 0.80
- MetaSVM 0.88
- CADD 27.40
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available