I118N (p.Ile118Asn) variant of DRD3 (Dopamine receptor D3)
I118N (p.Ile118Asn) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
I118N (p.Ile118Asn) variant details
- p.Ile118Asn
- gnomAD rs1396583854
- Missense
- Variant Prioritization Score for Impact Estimate 0.812
- REVEL 0.88
- ESM-1b 1.00
- AlphaMissense 0.99
- MetaLR 0.77
- MetaSVM 0.82
- CADD 28.30
- Most common in the African/African-American population (allele frequency 9e-05)
- Structural context available