I101S (p.Ile101Ser) variant of DRD3 (Dopamine receptor D3)
I101S (p.Ile101Ser) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes structural context.
I101S (p.Ile101Ser) variant details
- p.Ile101Ser
- Ensembl rs886057789
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.49
- ESM-1b 1.00
- AlphaMissense 0.13
- MetaLR 0.38
- MetaSVM -0.33
- SIFT 0.01
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available