G22S (p.Gly22Ser) variant of DRD3 (Dopamine receptor D3)
G22S (p.Gly22Ser) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G22S (p.Gly22Ser) variant details
- p.Gly22Ser
- Ensembl rs2077848719
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.32
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.16
- MetaSVM -0.86
- CADD 12.90
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available