G16W (p.Gly16Trp) variant of DRD3 (Dopamine receptor D3)
G16W (p.Gly16Trp) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G16W (p.Gly16Trp) variant details
- p.Gly16Trp
- gnomAD rs1228725780
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.19
- MetaSVM -0.91
- CADD 19.50
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available