F106C (p.Phe106Cys) variant of DRD3 (Dopamine receptor D3)
F106C (p.Phe106Cys) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes structural context.
F106C (p.Phe106Cys) variant details
- p.Phe106Cys
- NCI-TCGA Cosmic COSV5567
- cosmic curated COSV55678
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.55
- ESM-1b 1.00
- AlphaMissense 0.96
- MetaLR 0.24
- MetaSVM -0.54
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available