C102T (p.Cys102Thr) variant of DRD3 (Dopamine receptor D3)
C102T (p.Cys102Thr) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
C102T (p.Cys102Thr) variant details
- p.Cys102Thr
- rs749923013
- ExAC rs749923013
- TOPMed rs749923013
- gnomAD rs749923013
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- AlphaMissense 0.12
- MetaLR 0.08
- MetaSVM -1.03
- PolyPhen-2 0.86
- SIFT 0.02
- MutPred 0.40
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available