A59V (p.Ala59Val) variant of DRD3 (Dopamine receptor D3)
A59V (p.Ala59Val) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
A59V (p.Ala59Val) variant details
- p.Ala59Val
- ExAC rs777136888
- TOPMed rs777136888
- gnomAD rs777136888
- Missense
- Variant Prioritization Score for Impact Estimate 0.493
- REVEL 0.47
- ESM-1b 0.97
- AlphaMissense 0.15
- MetaLR 0.41
- MetaSVM -0.08
- CADD 22.90
- Most common in the African/African-American population (allele frequency 0.00043)
- Structural context available