A59T (p.Ala59Thr) variant of DRD3 (Dopamine receptor D3)
A59T (p.Ala59Thr) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A59T (p.Ala59Thr) variant details
- p.Ala59Thr
- TOPMed rs1442401537
- gnomAD rs1442401537
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.08
- ESM-1b 1.00
- AlphaMissense 0.09
- MetaLR 0.20
- MetaSVM -0.76
- CADD 14.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available