A38S (p.Ala38Ser) variant of DRD3 (Dopamine receptor D3)
A38S (p.Ala38Ser) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes structural context.
A38S (p.Ala38Ser) variant details
- p.Ala38Ser
- cosmic curated COSV10515
- 1000Genomes rs138354054
- ESP rs138354054
- ExAC rs138354054
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.12
- MetaLR 0.05
- MetaSVM -1.03
- SIFT 0.00
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available