A2T (p.Ala2Thr) variant of DRD3 (Dopamine receptor D3)
A2T (p.Ala2Thr) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- ExAC rs760223628
- TOPMed rs760223628
- gnomAD rs760223628
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.16
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.17
- MetaSVM -0.91
- CADD 22.40
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available