A17S (p.Ala17Ser) variant of DRD3 (Dopamine receptor D3)
A17S (p.Ala17Ser) in DRD3 (Dopamine receptor D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
A17S (p.Ala17Ser) variant details
- p.Ala17Ser
- ESP rs373701434
- ExAC rs373701434
- TOPMed rs373701434
- gnomAD rs373701434
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.15
- MetaSVM -0.99
- CADD 5.45
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available