A116S (p.Ala116Ser) variant of DRD3 (Dopamine receptor D3)
A116S (p.Ala116Ser) in DRD3 (Dopamine receptor D3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes structural context.
A116S (p.Ala116Ser) variant details
- p.Ala116Ser
- NCI-TCGA Cosmic COSV9987
- cosmic curated COSV99879
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.784
- REVEL 0.82
- ESM-1b 1.00
- AlphaMissense 0.24
- MetaLR 0.74
- MetaSVM 0.75
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available