Y37C (p.Tyr37Cys) variant of DRD2 (D(2) dopamine receptor)
Y37C (p.Tyr37Cys) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
Y37C (p.Tyr37Cys) variant details
- p.Tyr37Cys
- ExAC rs752405585
- gnomAD rs752405585
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.47
- MetaLR 0.16
- MetaSVM -0.85
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available