V91F (p.Val91Phe) variant of DRD2 (D(2) dopamine receptor)
V91F (p.Val91Phe) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V91F (p.Val91Phe) variant details
- p.Val91Phe
- ExAC rs773154659
- gnomAD rs773154659
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.20
- MetaLR 0.19
- MetaSVM -0.79
- CADD 25.70
- PolyPhen-2 0.64
- SIFT 0.01
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available