V87I (p.Val87Ile) variant of DRD2 (D(2) dopamine receptor)
V87I (p.Val87Ile) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
V87I (p.Val87Ile) variant details
- p.Val87Ile
- gnomAD rs1223999377
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.49
- MetaLR 0.58
- MetaSVM 0.19
- CADD 24.90
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available