V59M (p.Val59Met) variant of DRD2 (D(2) dopamine receptor)
V59M (p.Val59Met) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
V59M (p.Val59Met) variant details
- p.Val59Met
- cosmic curated COSV60753
- Missense
- Variant Prioritization Score for Impact Estimate 0.596
- REVEL 0.47
- MetaLR 0.47
- MetaSVM 0.36
- CADD 26.60
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available