T153I (p.Thr153Ile) variant of DRD2 (D(2) dopamine receptor)
T153I (p.Thr153Ile) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
T153I (p.Thr153Ile) variant details
- p.Thr153Ile
- cosmic curated COSV10525
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.29
- MetaLR 0.17
- MetaSVM -0.90
- CADD 26.00
- PolyPhen-2 0.77
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available