T134I (p.Thr134Ile) variant of DRD2 (D(2) dopamine receptor)
T134I (p.Thr134Ile) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
T134I (p.Thr134Ile) variant details
- p.Thr134Ile
- ESP rs370100350
- ExAC rs370100350
- TOPMed rs370100350
- gnomAD rs370100350
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.29
- MetaLR 0.17
- MetaSVM -0.97
- CADD 25.50
- PolyPhen-2 0.97
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available