S7F (p.Ser7Phe) variant of DRD2 (D(2) dopamine receptor)
S7F (p.Ser7Phe) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
S7F (p.Ser7Phe) variant details
- p.Ser7Phe
- Ensembl rs780510016
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.23
- MetaLR 0.24
- MetaSVM -0.76
- CADD 22.60
- PolyPhen-2 0.04
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available