S147N (p.Ser147Asn) variant of DRD2 (D(2) dopamine receptor)
S147N (p.Ser147Asn) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S147N (p.Ser147Asn) variant details
- p.Ser147Asn
- gnomAD rs1266929426
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.15
- MetaLR 0.19
- MetaSVM -0.80
- CADD 25.00
- PolyPhen-2 0.81
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available