S103I (p.Ser103Ile) variant of DRD2 (D(2) dopamine receptor)
S103I (p.Ser103Ile) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
S103I (p.Ser103Ile) variant details
- p.Ser103Ile
- TOPMed rs1395977945
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- REVEL 0.56
- MetaLR 0.33
- MetaSVM -0.11
- CADD 24.70
- SIFT 0.03
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available