R20P (p.Arg20Pro) variant of DRD2 (D(2) dopamine receptor)
R20P (p.Arg20Pro) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
R20P (p.Arg20Pro) variant details
- p.Arg20Pro
- ExAC rs199932425
- TOPMed rs199932425
- gnomAD rs199932425
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.11
- MetaLR 0.06
- MetaSVM -1.08
- CADD 22.40
- PolyPhen-2 0.18
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available