R151Q (p.Arg151Gln) variant of DRD2 (D(2) dopamine receptor)
R151Q (p.Arg151Gln) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R151Q (p.Arg151Gln) variant details
- p.Arg151Gln
- TOPMed rs1950833466
- gnomAD rs1950833466
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- REVEL 0.58
- MetaLR 0.37
- MetaSVM -0.11
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available