R150C (p.Arg150Cys) variant of DRD2 (D(2) dopamine receptor)
R150C (p.Arg150Cys) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
R150C (p.Arg150Cys) variant details
- p.Arg150Cys
- cosmic curated COSV60754
- ExAC rs754343100
- TOPMed rs754343100
- gnomAD rs754343100
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.43
- MetaLR 0.34
- MetaSVM -0.27
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available