P3L (p.Pro3Leu) variant of DRD2 (D(2) dopamine receptor)
P3L (p.Pro3Leu) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P3L (p.Pro3Leu) variant details
- p.Pro3Leu
- cosmic curated COSV60760
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.21
- MetaLR 0.20
- MetaSVM -0.84
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available