P139T (p.Pro139Thr) variant of DRD2 (D(2) dopamine receptor)
P139T (p.Pro139Thr) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
P139T (p.Pro139Thr) variant details
- p.Pro139Thr
- TOPMed rs1950833967
- Missense
- Variant Prioritization Score for Impact Estimate 0.754
- REVEL 0.76
- MetaLR 0.58
- MetaSVM 0.49
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available