M88I (p.Met88Ile) variant of DRD2 (D(2) dopamine receptor)
M88I (p.Met88Ile) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
M88I (p.Met88Ile) variant details
- p.Met88Ile
- gnomAD rs1489650563
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- REVEL 0.44
- MetaLR 0.44
- MetaSVM -0.26
- CADD 23.60
- PolyPhen-2 0.33
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available