M57V (p.Met57Val) variant of DRD2 (D(2) dopamine receptor)
M57V (p.Met57Val) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
M57V (p.Met57Val) variant details
- p.Met57Val
- ExAC rs769905247
- gnomAD rs769905247
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.08
- MetaLR 0.07
- MetaSVM -1.08
- CADD 21.00
- PolyPhen-2 0.09
- SIFT 0.46
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available