M57T (p.Met57Thr) variant of DRD2 (D(2) dopamine receptor)
M57T (p.Met57Thr) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
M57T (p.Met57Thr) variant details
- p.Met57Thr
- cosmic curated COSV10591
- gnomAD rs1349300395
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.38
- MetaLR 0.13
- MetaSVM -0.94
- CADD 25.60
- PolyPhen-2 0.67
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available