M140V (p.Met140Val) variant of DRD2 (D(2) dopamine receptor)
M140V (p.Met140Val) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M140V (p.Met140Val) variant details
- p.Met140Val
- ESP rs377059381
- ExAC rs377059381
- gnomAD rs377059381
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.12
- MetaLR 0.05
- MetaSVM -1.08
- CADD 17.10
- PolyPhen-2 0.04
- SIFT 0.80
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available