K28R (p.Lys28Arg) variant of DRD2 (D(2) dopamine receptor)
K28R (p.Lys28Arg) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
K28R (p.Lys28Arg) variant details
- p.Lys28Arg
- ExAC rs200802757
- TOPMed rs200802757
- gnomAD rs200802757
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.00
- CADD 8.64
- PolyPhen-2 0.04
- SIFT 0.35
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available