K28Q (p.Lys28Gln) variant of DRD2 (D(2) dopamine receptor)
K28Q (p.Lys28Gln) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K28Q (p.Lys28Gln) variant details
- p.Lys28Gln
- gnomAD rs1179668690
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -0.99
- CADD 11.70
- PolyPhen-2 0.01
- SIFT 0.44
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available