I158V (p.Ile158Val) variant of DRD2 (D(2) dopamine receptor)
I158V (p.Ile158Val) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I158V (p.Ile158Val) variant details
- p.Ile158Val
- 1000Genomes rs139000780
- ESP rs139000780
- ExAC rs139000780
- gnomAD rs139000780
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.07
- MetaLR 0.02
- MetaSVM -1.02
- CADD 15.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available