I128V (p.Ile128Val) variant of DRD2 (D(2) dopamine receptor)
I128V (p.Ile128Val) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
I128V (p.Ile128Val) variant details
- p.Ile128Val
- ESP rs372879445
- ExAC rs372879445
- TOPMed rs372879445
- gnomAD rs372879445
- Missense
- Variant Prioritization Score for Impact Estimate 0.695
- REVEL 0.76
- MetaLR 0.63
- MetaSVM 0.41
- CADD 25.80
- PolyPhen-2 0.64
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available