E62D (p.Glu62Asp) variant of DRD2 (D(2) dopamine receptor)
E62D (p.Glu62Asp) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
E62D (p.Glu62Asp) variant details
- p.Glu62Asp
- Ensembl rs1950918416
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- REVEL 0.38
- MetaLR 0.50
- MetaSVM 0.01
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available