D10N (p.Asp10Asn) variant of DRD2 (D(2) dopamine receptor)
D10N (p.Asp10Asn) in DRD2 (D(2) dopamine receptor) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
D10N (p.Asp10Asn) variant details
- p.Asp10Asn
- NCI-TCGA Cosmic COSV1006
- cosmic curated COSV10066
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.08
- MetaLR 0.14
- MetaSVM -0.93
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.86
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available