D10H (p.Asp10His) variant of DRD2 (D(2) dopamine receptor)
D10H (p.Asp10His) in DRD2 (D(2) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
D10H (p.Asp10His) variant details
- p.Asp10His
- ExAC rs752635005
- gnomAD rs752635005
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.27
- MetaLR 0.24
- MetaSVM -0.60
- CADD 24.20
- PolyPhen-2 0.54
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available